| Company Name: |
Alfa Aesar |
| Tel: |
400-6106006 |
| Email: |
saleschina@alfa-asia.com |
- BOC-ABU-OH
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- $999.00
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2026-10-29
- CAS:34306-42-8
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 5000
- BOC-ABU-OH
-
- $1.00
-
2026-10-10
- CAS:34306-42-8
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 20T
- Boc-L-2-Abu-OH
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-
2026-09-30
- CAS:34306-42-8
- Min. Order: 1kg
- Purity: 98%
- Supply Ability: 1T+
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| | Boc-Abu-OH Chemical Properties |
| Melting point | 70-74 °C | | Boiling point | 334.5±25.0 °C(Predicted) | | density | 1.101±0.06 g/cm3(Predicted) | | Fp | 113 °C | | storage temp. | Keep in dark place,Sealed in dry,Room Temperature | | form | Solid | | pka | 4.00±0.10(Predicted) | | color | White to Almost white | | Optical Rotation | [α]20/D 18.5±2°, c = 1% in methanol | | Water Solubility | Slightly soluble in water. | | BRN | 6801706 | | Major Application | peptide synthesis | | InChI | InChI=1S/C9H17NO4/c1-5-6(7(11)12)10-8(13)14-9(2,3)4/h6H,5H2,1-4H3,(H,10,13)(H,11,12)/t6-/m0/s1 | | InChIKey | PNFVIPIQXAIUAY-LURJTMIESA-N | | SMILES | C(O)(=O)[C@@H](NC(OC(C)(C)C)=O)CC | | CAS DataBase Reference | 34306-42-8(CAS DataBase Reference) |
| Risk Statements | 36/37/38 | | Safety Statements | 4-7-28-35-44 | | WGK Germany | 3 | | HazardClass | IRRITANT | | HS Code | 29241990 | | Storage Class | 11 - Combustible Solids |
| | Boc-Abu-OH Usage And Synthesis |
| Preparation | BOC-ABU-OH is generally synthesized from DL-2-aminobutyric acid. The specific synthesis steps are as follows: 10.3 g of DL-2-aminobutyric acid is dissolved in a mixture of 95 mL of 1 M NaOH solution and 65 mL of methanol. 27.5 mL of di-tert-butyl dicarbonate (i.e., Boc anhydride, 1.2 eq.) is added in an ice bath, and the mixture is slowly heated to room temperature with stirring for 12 hours. After the reaction is complete, methanol is removed by rotary evaporation, the pH is adjusted to 1-2 with 1 M hydrochloric acid, and the mixture is extracted with ethyl acetate (50 mL x 3), washed with saturated brine (40 mL x 2), and dehydrated with anhydrous sodium sulfate. Finally, rotary evaporation yields 18.9 g of colorless solid (93.4%). | | Chemical Properties | Light yellow powder | | Uses | It is employed as a intermediate for pharmaceutical. | | reaction suitability | reaction type: Boc solid-phase peptide synthesis |
| | Boc-Abu-OH Preparation Products And Raw materials |
| Raw materials | Butanoic acid, 2-[[(1,1-dimethylethoxy)carbonyl]amino]-, methyl ester, (2R)--->Butanoic acid, 2-[[(1,1-diMethylethoxy)carbonyl]aMino]-, Methyl ester-->L(+)-2-Aminobutyric acid-->Boc-L-vinylglycine-->Di-tert-butyl dicarbonate | | Preparation Products | Boc-D-Abu-OH-->Carbamic acid, [(1S)-1-(aminocarbonyl)propyl]-, 1,1-dimethylethyl ester (9CI)-->1-?Butanone, 1,?1'-?[(6,?6'-?difluoro[2,?2'-?bi-?1H-?indole]?-?3,?3'-?diyl)?bis[methylene[(2R,?4S)?-?4-?(acetyloxy)?-?2,?1-?pyrrolidinediyl]?]?]?bis[2-?amino-?, (2S,?2'S)?- |
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